USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: CATA_HUMAN USC-OGP 2-DE database:  CATA_HUMAN CATA_HUMAN General information about the entry View entry in simple text format Entry name CATA_HUMAN Primary accession number P04040 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Catalase; EC=1.11.1.6;. Gene name Name=CAT Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0888: pI=6.90; Mw=57393 SPOT OGP-0889: pI=6.86; Mw=57238 Cross-references UniProtKB/Swiss-Prot P04040; CATA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CATA_HUMAN Primary accession number P04040 Secondary accession number(s) A8K6C0 B2RCZ9 D3DR07 Q2M1U4 Q4VXX5 Q9BWT9 Q9UC85 Sequence was last modified on  January 23, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 196) Name and origin of the protein Description RecName: Full=Catalase; EC=1.11.1.6; Gene name Name=CAT Encoded on Name=CAT Keywords 3D-structure; Acetylation; Complete proteome; Direct protein sequencing; Heme; Hydrogen peroxide; Iron; Metal-binding; Mitogen; NADP; Oxidoreductase; Peroxidase; Peroxisome; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X04085; CAA27721.1; -; Genomic_DNA EMBL X04086; CAA27721.1; JOINED; Genomic_DNA EMBL X04087; CAA27721.1; JOINED; Genomic_DNA EMBL X04088; CAA27721.1; JOINED; Genomic_DNA EMBL X04089; CAA27721.1; JOINED; Genomic_DNA EMBL X04090; CAA27721.1; JOINED; Genomic_DNA EMBL X04091; CAA27721.1; JOINED; Genomic_DNA EMBL X04092; CAA27721.1; JOINED; Genomic_DNA EMBL X04093; CAA27721.1; JOINED; Genomic_DNA EMBL X04094; CAA27721.1; JOINED; Genomic_DNA EMBL X04095; CAA27721.1; JOINED; Genomic_DNA EMBL X04096; CAA27721.1; JOINED; Genomic_DNA EMBL X04076; CAA27717.1; -; mRNA EMBL AY028632; AAK29181.1; -; mRNA EMBL AK291585; BAF84274.1; -; mRNA EMBL AK315350; BAG37746.1; -; mRNA EMBL AY545477; AAS37679.1; -; Genomic_DNA EMBL AL035079; CAB45236.1; -; Genomic_DNA EMBL CH471064; EAW68170.1; -; Genomic_DNA EMBL CH471064; EAW68171.1; -; Genomic_DNA EMBL BC110398; AAI10399.1; -; mRNA EMBL BC112217; AAI12218.1; -; mRNA EMBL BC112219; AAI12220.1; -; mRNA EMBL L13609; AAA16651.1; -; Genomic_DNA EMBL K02400; AAB59522.1; -; Genomic_DNA CCDS CCDS7891.1; -; . PIR A23646; CSHU; . RefSeq NP_001743.1; NM_001752.3; . UniGene Hs.502302; -; . PDB 1DGB; X-ray; 2.20 A; A/B/C/D=4-501 PDB 1DGF; X-ray; 1.50 A; A/B/C/D=5-501 PDB 1DGG; X-ray; 1.80 A; A/B/C/D=5-501 PDB 1DGH; X-ray; 2.00 A; A/B/C/D=4-501 PDB 1F4J; X-ray; 2.40 A; A/B/C/D=1-527 PDB 1QQW; X-ray; 2.75 A; A/B/C/D=1-527 PDBsum 1DGB; -; . PDBsum 1DGF; -; . PDBsum 1DGG; -; . PDBsum 1DGH; -; . PDBsum 1F4J; -; . PDBsum 1QQW; -; . ProteinModelPortal P04040; -; . SMR P04040; -; . BioGrid 107297; 48; . IntAct P04040; 21; . MINT MINT-1210583; -; . STRING 9606.ENSP00000241052; -; . ChEMBL CHEMBL3627594; -; . DrugBank DB01213; Fomepizole; . PeroxiBase 5282; HsKat01; . iPTMnet P04040; -; . PhosphoSitePlus P04040; -; . SwissPalm P04040; -; . BioMuta CAT; -; . DMDM 115702; -; . OGP P04040; -; . REPRODUCTION-2DPAGE IPI00465436; -; . REPRODUCTION-2DPAGE P04040; -; . SWISS-2DPAGE P04040; -; . EPD P04040; -; . MaxQB P04040; -; . PaxDb P04040; -; . PeptideAtlas P04040; -; . PRIDE P04040; -; . DNASU 847; -; . Ensembl ENST00000241052; ENSP00000241052; ENSG00000121691; . GeneID 847; -; . KEGG hsa:847; -; . UCSC uc001mvm.4; human; . CTD 847; -; . DisGeNET 847; -; . GeneCards CAT; -; . H-InvDB HIX0009550; -; . HGNC HGNC:1516; CAT; . HPA CAB001515; -; . HPA HPA051282; -; . HPA HPA055838; -; . MalaCards CAT; -; . MIM 115500; gene; . MIM 614097; phenotype; . neXtProt NX_P04040; -; . OpenTargets ENSG00000121691; -; . Orphanet 926; Acatalasemia; . PharmGKB PA26099; -; . eggNOG KOG0047; Eukaryota; . eggNOG COG0753; LUCA; . GeneTree ENSGT00390000018100; -; . HOVERGEN HBG003986; -; . InParanoid P04040; -; . KO K03781; -; . OMA WDYRADD; -; . OrthoDB EOG091G04V5; -; . PhylomeDB P04040; -; . TreeFam TF300540; -; . BioCyc MetaCyc:MONOMER66-341; -; . BRENDA 1.11.1.6; 2681; . Reactome R-HSA-3299685; Detoxification of Reactive Oxygen Species; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-74259; Purine catabolism; . SABIO-RK P04040; -; . SIGNOR P04040; -; . ChiTaRS CAT; human; . EvolutionaryTrace P04040; -; . GeneWiki Catalase; -; . GenomeRNAi 847; -; . PRO PR:P04040; -; . Proteomes UP000005640; Chromosome 11; . Bgee ENSG00000121691; -; . CleanEx HS_CAT; -; . Genevisible P04040; HS; . GO GO:0005829; C:cytosol; IEA:Ensembl; . GO GO:0005783; C:endoplasmic reticulum; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005615; C:extracellular space; IEA:Ensembl; . GO GO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0005794; C:Golgi apparatus; IEA:Ensembl; . GO GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA; . GO GO:0005764; C:lysosome; IEA:Ensembl; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005758; C:mitochondrial intermembrane space; IEA:Ensembl; . GO GO:0005739; C:mitochondrion; IBA:GO_Central; . GO GO:0005782; C:peroxisomal matrix; TAS:Reactome; . GO GO:0005778; C:peroxisomal membrane; ISS:UniProtKB; . GO GO:0005777; C:peroxisome; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IEA:Ensembl; . GO GO:0034774; C:secretory granule lumen; TAS:Reactome; . GO GO:0004046; F:aminoacylase activity; IEA:Ensembl; . GO GO:0016209; F:antioxidant activity; IDA:UniProtKB; . GO GO:0004096; F:catalase activity; IDA:UniProtKB; . GO GO:0019899; F:enzyme binding; IPI:UniProtKB; . GO GO:0020037; F:heme binding; IDA:UniProtKB; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0050661; F:NADP binding; IDA:UniProtKB; . GO GO:0016684; F:oxidoreductase activity; acting on peroxide as acceptor; ISS:UniProtKB GO GO:0042803; F:protein homodimerization activity; IDA:UniProtKB; . GO GO:0005102; F:receptor binding; IPI:UniProtKB; . GO GO:0009060; P:aerobic respiration; IEA:Ensembl; . GO GO:0007568; P:aging; IEA:Ensembl; . GO GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl; . GO GO:0008203; P:cholesterol metabolic process; IEA:Ensembl; . GO GO:0020027; P:hemoglobin metabolic process; IEA:Ensembl; . GO GO:0042744; P:hydrogen peroxide catabolic process; IDA:UniProtKB; . GO GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB; . GO GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IEA:Ensembl; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . GO GO:0001649; P:osteoblast differentiation; IDA:UniProtKB; . GO GO:0051781; P:positive regulation of cell division; IEA:UniProtKB-KW; . GO GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IEA:Ensembl; . GO GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase signaling; IEA:Ensembl; . GO GO:0051289; P:protein homotetramerization; IDA:UniProtKB; . GO GO:0051262; P:protein tetramerization; IDA:UniProtKB; . GO GO:0006195; P:purine nucleotide catabolic process; TAS:Reactome; . GO GO:0014823; P:response to activity; IEA:Ensembl; . GO GO:0046686; P:response to cadmium ion; IEA:Ensembl; . GO GO:0042493; P:response to drug; IEA:Ensembl; . GO GO:0032355; P:response to estradiol; IEA:Ensembl; . GO GO:0045471; P:response to ethanol; IEA:Ensembl; . GO GO:0070542; P:response to fatty acid; IEA:Ensembl; . GO GO:0042542; P:response to hydrogen peroxide; IBA:GO_Central; . GO GO:0055093; P:response to hyperoxia; IEA:Ensembl; . GO GO:0001666; P:response to hypoxia; IEA:Ensembl; . GO GO:0014854; P:response to inactivity; IEA:Ensembl; . GO GO:0032868; P:response to insulin; IEA:Ensembl; . GO GO:0033591; P:response to L-ascorbic acid; IEA:Ensembl; . GO GO:0010288; P:response to lead ion; IEA:Ensembl; . GO GO:0009642; P:response to light intensity; IEA:Ensembl; . GO GO:0010193; P:response to ozone; IEA:Ensembl; . GO GO:0080184; P:response to phenylpropanoid; IEA:Ensembl; . GO GO:0000302; P:response to reactive oxygen species; IMP:UniProtKB; . GO GO:0033189; P:response to vitamin A; IEA:Ensembl; . GO GO:0033197; P:response to vitamin E; IEA:Ensembl; . GO GO:0006641; P:triglyceride metabolic process; IEA:Ensembl; . GO GO:0001657; P:ureteric bud development; IEA:Ensembl; . GO GO:0009650; P:UV protection; IMP:UniProtKB; . Gene3D 2.40.180.10; -; 1; . InterPro IPR018028; Catalase; . InterPro IPR020835; Catalase-like_dom; . InterPro IPR024708; Catalase_AS; . InterPro IPR024711; Catalase_clade1/3; . InterPro IPR011614; Catalase_core; . InterPro IPR002226; Catalase_haem_BS; . InterPro IPR010582; Catalase_immune_responsive; . PANTHER PTHR11465; PTHR11465; 1; . Pfam PF00199; Catalase; 1; . Pfam PF06628; Catalase-rel; 1; . PIRSF PIRSF038928; Catalase_clade1-3; 1; . PRINTS PR00067; CATALASE; . SMART SM01060; Catalase; 1; . SUPFAM SSF56634; SSF56634; 1; . PROSITE PS00437; CATALASE_1; 1; . PROSITE PS00438; CATALASE_2; 1; . PROSITE PS51402; CATALASE_3; 1; .

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• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
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